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Sangon Biotech cleaved-off of type i collagen (pinp)
AC reverses the high bone turnover makers and remodels the osteoporotic pathophysiological microenvironment in OVX mice. Serum levels of bone formation markers of (A) bone-specific alkaline (BALP) and (B) N-terminal propeptide of type I collagen <t>(PINP).</t> (C) Serum β-CTX levels of the bone resorption marker. n = 6. IHC staining of (D) Runx2 and (E) Osterix in the lumbar vertebrae of each group. The red arrows represented the positive expression. (F) Representative of TRAP staining among groups. The black arrows represented the TRAP-positive cells. (G, H) Quantification of Runx2 + and Osterix + cells. n = 4. (I) The ratio of the number of osteoclasts to per unit bone surface (OC.N/BS). n = 6. Data presented as means ± s.d. * P < 0.05, ** P < 0.01, *** P < 0.001.
Cleaved Off Of Type I Collagen (Pinp), supplied by Sangon Biotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cleaved-off of type i collagen (pinp)/product/Sangon Biotech
Average 90 stars, based on 1 article reviews
cleaved-off of type i collagen (pinp) - by Bioz Stars, 2026-03
90/100 stars

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1) Product Images from "Aconine attenuates osteoclast-mediated bone resorption and ferroptosis to improve osteoporosis via inhibiting NF-κB signaling"

Article Title: Aconine attenuates osteoclast-mediated bone resorption and ferroptosis to improve osteoporosis via inhibiting NF-κB signaling

Journal: Frontiers in Endocrinology

doi: 10.3389/fendo.2023.1234563

AC reverses the high bone turnover makers and remodels the osteoporotic pathophysiological microenvironment in OVX mice. Serum levels of bone formation markers of (A) bone-specific alkaline (BALP) and (B) N-terminal propeptide of type I collagen (PINP). (C) Serum β-CTX levels of the bone resorption marker. n = 6. IHC staining of (D) Runx2 and (E) Osterix in the lumbar vertebrae of each group. The red arrows represented the positive expression. (F) Representative of TRAP staining among groups. The black arrows represented the TRAP-positive cells. (G, H) Quantification of Runx2 + and Osterix + cells. n = 4. (I) The ratio of the number of osteoclasts to per unit bone surface (OC.N/BS). n = 6. Data presented as means ± s.d. * P < 0.05, ** P < 0.01, *** P < 0.001.
Figure Legend Snippet: AC reverses the high bone turnover makers and remodels the osteoporotic pathophysiological microenvironment in OVX mice. Serum levels of bone formation markers of (A) bone-specific alkaline (BALP) and (B) N-terminal propeptide of type I collagen (PINP). (C) Serum β-CTX levels of the bone resorption marker. n = 6. IHC staining of (D) Runx2 and (E) Osterix in the lumbar vertebrae of each group. The red arrows represented the positive expression. (F) Representative of TRAP staining among groups. The black arrows represented the TRAP-positive cells. (G, H) Quantification of Runx2 + and Osterix + cells. n = 4. (I) The ratio of the number of osteoclasts to per unit bone surface (OC.N/BS). n = 6. Data presented as means ± s.d. * P < 0.05, ** P < 0.01, *** P < 0.001.

Techniques Used: Marker, Immunohistochemistry, Expressing, Staining



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Sangon Biotech cleaved-off of type i collagen (pinp)
AC reverses the high bone turnover makers and remodels the osteoporotic pathophysiological microenvironment in OVX mice. Serum levels of bone formation markers of (A) bone-specific alkaline (BALP) and (B) N-terminal propeptide of type I collagen <t>(PINP).</t> (C) Serum β-CTX levels of the bone resorption marker. n = 6. IHC staining of (D) Runx2 and (E) Osterix in the lumbar vertebrae of each group. The red arrows represented the positive expression. (F) Representative of TRAP staining among groups. The black arrows represented the TRAP-positive cells. (G, H) Quantification of Runx2 + and Osterix + cells. n = 4. (I) The ratio of the number of osteoclasts to per unit bone surface (OC.N/BS). n = 6. Data presented as means ± s.d. * P < 0.05, ** P < 0.01, *** P < 0.001.
Cleaved Off Of Type I Collagen (Pinp), supplied by Sangon Biotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cleaved-off of type i collagen (pinp)/product/Sangon Biotech
Average 90 stars, based on 1 article reviews
cleaved-off of type i collagen (pinp) - by Bioz Stars, 2026-03
90/100 stars
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AC reverses the high bone turnover makers and remodels the osteoporotic pathophysiological microenvironment in OVX mice. Serum levels of bone formation markers of (A) bone-specific alkaline (BALP) and (B) N-terminal propeptide of type I collagen (PINP). (C) Serum β-CTX levels of the bone resorption marker. n = 6. IHC staining of (D) Runx2 and (E) Osterix in the lumbar vertebrae of each group. The red arrows represented the positive expression. (F) Representative of TRAP staining among groups. The black arrows represented the TRAP-positive cells. (G, H) Quantification of Runx2 + and Osterix + cells. n = 4. (I) The ratio of the number of osteoclasts to per unit bone surface (OC.N/BS). n = 6. Data presented as means ± s.d. * P < 0.05, ** P < 0.01, *** P < 0.001.

Journal: Frontiers in Endocrinology

Article Title: Aconine attenuates osteoclast-mediated bone resorption and ferroptosis to improve osteoporosis via inhibiting NF-κB signaling

doi: 10.3389/fendo.2023.1234563

Figure Lengend Snippet: AC reverses the high bone turnover makers and remodels the osteoporotic pathophysiological microenvironment in OVX mice. Serum levels of bone formation markers of (A) bone-specific alkaline (BALP) and (B) N-terminal propeptide of type I collagen (PINP). (C) Serum β-CTX levels of the bone resorption marker. n = 6. IHC staining of (D) Runx2 and (E) Osterix in the lumbar vertebrae of each group. The red arrows represented the positive expression. (F) Representative of TRAP staining among groups. The black arrows represented the TRAP-positive cells. (G, H) Quantification of Runx2 + and Osterix + cells. n = 4. (I) The ratio of the number of osteoclasts to per unit bone surface (OC.N/BS). n = 6. Data presented as means ± s.d. * P < 0.05, ** P < 0.01, *** P < 0.001.

Article Snippet: The cleaved-off of type I collagen (PINP) (Sangon Biotech, D721053) and bone-specific alkaline phosphatase (BALP) (Sangon Biotech, D721049) were performed for bone formation, while carboxy-terminal cross-linking telopeptide of type I collagen (β-CTX) (Sangon Biotech, D721187) was detected for bone resorption.

Techniques: Marker, Immunohistochemistry, Expressing, Staining